International Journal of Pharmaceutical Chemistry
Our mission is to advance the science and practice of
pharmaceutical chemistry by working to develop and maintain
competence, ethics and integrity and the highest
professional standards in the specialty for the benefit of
the public. The Faculty seeks, through its activities, to
bring about an improvement in the health of the public.
The International Journal of Pharmaceutical
Chemistrypublishes studies that contribute to an
understanding of the relationship between molecular
structure and biological activity or mode of action.
Some specific areas that are appropriate include the
Design, synthesis, and biological evaluation of novel
biologically active compounds, diagnostic agents, or labeled
ligands employed as pharmacological tools.
Molecular modifications of reported series that lead to a
significantly improved understanding of their structure-
activity relationships (SAR). Routine extensions of existing
series that do not utilize novel chemical or biological
approaches or do not add significantly to a basic
understanding of the SAR of the series will normally not be
accepted for publication.
Structural biological studies (X-ray, NMR, etc.) of relevant
ligands and targets with the aim of investigating molecular
recognition processes in the action of biologically active
Molecular biological studies (e.g., site-directed
mutagenesis) of macromolecular targets that lead to an
improved understanding of molecular recognition.
Computational studies that provide fresh insight into the
SAR of compound series that are of current general interest
or analysis of other available data that subsequently
advance medicinal chemistry knowledge.
Substantially novel computational chemistry methods with
demonstrated value for the identification, optimization, or
target interaction analysis of bioactive molecules.
Effect of molecular structure on the distribution,
pharmacokinetics, and metabolic transformation of
biologically active compounds. This may include design,
synthesis, and evaluation of novel types of prodrugs.
Novel methodology with broad application to medicinal
chemistry, but only if the methods have been tested on
Contact: Editor in Chief
Subject: Pharmaceutical Chemistry
Date Posted: 23rd January, 2013