Journal of Autoimmune Diseases (JAD)
Publisher: BioMed Central
Journal of Autoimmune Diseases is a new, on-line journal created for the
rapid publication of, and open access to, scientific reports in the
field of autoimmunity.
What is autoimmune research?
An erroneous recognition of self by the immune system underlies a number
of human diseases, termed autoimmune. These include Type 1 (juvenile)
diabetes mellitus, rheumatoid arthritis, thyroiditis, and multiple
sclerosis, as well as others. A better understanding of autoimmunity
depends on the progress made in scientific fields such as molecular and
cell biology, genetics, pharmacology, and environmental biology. Novel
approaches for treating patients with autoimmune diseases have been
developed, including selective immunosuppressive drugs, peptide and DNA
vaccines, transplantation, trans-differentiation, and regeneration.
Research in autoimmunity, therefore, is broad-based, and addresses
questions both of the effector (i.e. immune) system and the target organs.
Although the ultimate aim of research in autoimmunity is the eradication
of autoimmune disorders, the limitations of human experiments mean that
various animal models are required. In the last three decades the key
concepts of autoimmune reactions have come from the animal studies,
usually from spontaneous and induced rodent models of human diseases.
For now, these remain the major method for testing new hypotheses and
The Journal of Autoimmune Diseases accepts reports on clinical and
experimental research in autoimmunity. The emphasis will be made on
studies that are relevant to the treatment of patients with autoimmune
diseases, but basic research that helps our understanding of immune
mechanisms leading to a mistake in recognition of self will also be
considered (either animal or human studies). Molecular, cellular and
whole organism levels will all be represented. We welcome manuscripts in
areas such as immunogenetics, immune cell signaling, molecular markers
of autoimmune diseases, immune interventions, new animal models,
transplantation, stem cell therapy, and gene therapy. The Journal will
publish high quality reports with mostly positive data, as well as
methodology papers, reviews, hypotheses, commentaries, and editorials.
"Open access" means that all our articles are freely and universally
accessible online, authors retain copyright, and all material is
immediately available in PubMed, as well as archived in PubMed Central.
To facilitate rapid publication and to minimize administrative costs,
Journal of Autoimmune Diseases accepts only online submission.
Dr David D’Cruz
The Rayne Institute, St Thomas' Hospital
Abstracts available online. Articles available in HTML and PDF format.
Current Issue: Volume 1:4 (19 November 2004)
Date: 21 Jan. 2005