Journal of Neuroinflammation
Publisher: BioMed Central
Journal of Neuroinflammation is an Open Access, peer-reviewed online journal
that focuses on innate immunological responses of the central nervous
system, involving microglia, astrocytes, cytokines, chemokines, and related
'Neuroinflammation' is an encapsulization of the idea that microglial and
astrocytic responses and actions in the central nervous system have a
fundamentally inflammation-like character, and that these responses are
central to the pathogenesis and progression of a wide variety of
This idea has revolutionized our understanding of Alzheimer's disease, where
it originated, and now has applications to other neurodegenerative diseases,
to ischemic/toxic diseases, and even to normal brain development.
Neuroinflammation incorporates a wide spectrum of complex cellular responses
that include microglia and astrocytes, cytokines and chemokines, complement
proteins, acute phase proteins, oxidative injury, and related molecular
Neuroinflammation is a new and rapidly expanding field that has
revolutionized our understanding of chronic neurological diseases. This
field has grown to encompass researchers with backgrounds in many diverse
fields, including pathology, biochemistry, molecular biology, genetics,
clinical medicine, and epidemiology.
Important contributions to this field have come from work with populations,
with patients, with postmortem tissues, with animal models, and with in
vitro systems. The Journal of Neuroinflammation will bring together work
focusing on common pathogenic processes, and provide a forum for integrative
reviews and commentaries on this field.
Journal of Neuroinflammation considers the following types of articles:
* Case reports: reports of clinical cases that can be educational, describe
a diagnostic or therapeutic dilemma, suggest an association, or present an
important adverse reaction. All case report articles should be accompanied
by written and signed consent to publish the information from the patients
or their guardians.
* Commentaries: short, focused and opinionated articles on any subject
within the journal's scope. These articles are usually related to a
contemporary issue, such as recent research findings. They focus on specific
issues and are about 800 words.
* Hypothesis: short articles presenting an untested original hypothesis
backed solely by previously published results rather than any new evidence.
They should outline significant progress in thinking that would also be
testable, and be about 1500 words.
vResearch: reports of data from original research.
* Reviews: comprehensive, authoritative, descriptions of any subject within
the journal's scope. They have an educational aim and are 2000-3000 words.
Short reports: brief reports of data from original research, usually about